ASCO 2024: Upcoming Treatment Innovations in Prostate Cancer

Sandy Srinivas, MD

Disclosures

May 23, 2024

Sandy Srinivas, MD, highlights several abstracts in prostate cancer to be presented at ASCO 2024. Notable among them are late-breaking studies, including CHAARTED 2, comparing cabazitaxel plus abiraterone vs abiraterone alone; the MAST study, examining metformin's impact on low-risk prostate cancer progression; and the MANCAN2 trial, investigating cognitive-behavioral therapy for managing hot flushes and night sweats.

Beyond this, health-related quality-of-life studies like PSMAfore and EMBARK will be spotlighted. While CYCLONE 2's negative findings on abemaciclib plus abiraterone will be discussed, attention will also be on emerging treatments such as ARV-766, a PROTAC androgen receptor degrader, and tarlatamab, targeting DLL3 for neuroendocrine prostate cancer.

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