Critical Issues

Beta-Blockers: Safe for COPD? Are beta-blockers bad for patients with COPD? Decades of debate and clinical trials have not settled the issue.
Viewpoint, July 23, 2024
The Tyranny of Beta-Blockers Providers are loath to mess with beta-blocker dosing, but with a little finesse, doctors can preserve the benefits of beta-blockers while helping patients meet their exercise goals.
Viewpoint, June 12, 2024
CPAP Underperforms: The Sequel Still room for CPAP in the cemetery for discarded medical therapies.
Viewpoint, May 15, 2024
Swimming in a Sea of Vancomycin and Piperacillin-Tazobactam Dr Aaron Holley questions the pervasive use of vancomycin and piperacillin-tazobactam combination therapy in the ICU.
Experts And Viewpoints, January 12, 2024
CPAP Oversells and Underperforms The pressure pushers have been undeterred by evidence, says Dr Holley.
Experts And Viewpoints, December 22, 2023
Role of Hydrocortisone, Fludrocortisone in Septic Shock Twenty years after abandoning hydro/fludro for septic shock, Dr Holley will use it again, with some reservations.
Experts And Viewpoints, November 20, 2023
Post-COVID Syndrome: Fatigue & Exercise Intolerance The authors of a new review know more about post-infection syndromes than does anyone else in the world and provide a must-read for all pulmonologists.
Experts And Viewpoints, October 11, 2023
When Does a Bicarb Drip Make Sense? An older woman is admitted to the ICU with acidosis, AKI, and ketonuria. Will IV bicarb help or harm?
Experts And Viewpoints, September 01, 2023
Lung Testing Insights: PRISm and Nonspecific Pattern PRISm and the nonspecific pattern are among the important updates in the recent statement on lung testing interpretation from ERS/ATS.
Experts And Viewpoints, August 04, 2023
Parsing the Split-Decision Victory for Biologics in COPD A single drug that works for COPD exacerbations would be welcome news, but studies of new monoclonal antibodies conflict, and Dr Aaron Holley still has a lot of questions.
Experts And Viewpoints, July 06, 2023
Antibiotics for AECOPD: It's Still Controversial The Rome criteria aren't evidence-based; rather, they're a necessary first step toward creating the evidence.
Experts And Viewpoints, June 06, 2023
Sleep, Circadian Rhythms, Delirium, and the ICU Dexmedetomidine is the current darling for improving sleep in patients in the ICU. But does the evidence support it?
Experts And Viewpoints, May 08, 2023
Treating Unexplained Dyspnea, Bendopnea, and HFpEF Unexplained bendopnea (yes, it's a thing) can be a sign of HFpEF, even without other symptoms.
Experts And Viewpoints, April 19, 2023
Fatigue Is a Monster for Patients With Pulmonary Disease Fatigue is common for patients with lung diseases, yet many guidelines give it short shrift or ignore it altogether.
Experts And Viewpoints, March 23, 2023
The Challenge of Incidental Interstitial Lung Abnormalities A recent study moves us closer to identifying a valid model for risk-stratifying incidental interstitial lung abnormalities, but we've still got a long way to go, says Dr Holley.
Experts And Viewpoints, January 27, 2023
AHRQ Highlights Uncertainty About OSA Definitions and Outcomes We still don't have a firm definition of OSA.
Experts And Viewpoints, January 10, 2023
Latest on Lung Function Guidelines, Bronchodilator Testing How much has changed in bronchodilator testing guidelines? Dr Aaron Holley reviews the current literature.
Experts And Viewpoints, December 08, 2022
ERS/ATS Lung Guidelines Endorse Global Lung Initiative Despite unresolved questions about the impact of race/ethnicity on lung function, the GLI explains a large portion of the variability in lung function testing.
Experts And Viewpoints, November 28, 2022
What's the Optimal Temp Management After Cardiac Arrest? Early adopters, beware of the litany of therapies that fail the scrutiny of multiple large RCTs.
Experts And Viewpoints, September 29, 2022
LAMA Takes a Hit in New Update We've heard this story before; LAMA monotherapy is the latest casualty of current asthma treatment.
Experts And Viewpoints, September 29, 2022

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